Article : Explicit memory creation during sleep demonstrates a causal role of place cells in navigation
  • Auteurs
    Gaetan de Lavilléon, Marie Masako Lacroix, Laure Rondi-Reig, Karim Benchenane
  • Année de publication
    2015
  • Journal
    Nature Neuroscience
  • Abstract (dans sa langue originale)

    Hippocampal place cells assemblies are believed to support the cognitive map, and their reactivations during sleep are thought to be involved in spatial memory consolidation. By triggering intracranial rewarding stimulations by place cell spikes during sleep, we induced an explicit memory trace, leading to a goal-directed behavior toward the place field. This demonstrates that place cells' activity during sleep still conveys relevant spatial information and that this activity is functionally significant for navigation.

  • Identifiant unique
    10.1038/nn.3970
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