Review : The neuroscience of placebo effects: connecting context, learning and health
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  • Auteurs
    Tor D. Wager, Lauren Y. Atlas
  • Année de publication
    2015
  • Journal
    Nature Reviews Neuroscience
  • Abstract (dans sa langue originale)

    Placebo effects are beneficial effects that are attributable to the brain–mind
    responses to the context in which a treatment is delivered rather than to the specific
    actions of the drug. They are mediated by diverse processes — including learning,
    expectations and social cognition — and can influence various clinical and physiological
    outcomes related to health. Emerging neuroscience evidence implicates multiple brain
    systems and neurochemical mediators, including opioids and dopamine. We present an
    empirical review of the brain systems that are involved in placebo effects, focusing on
    placebo analgesia, and a conceptual framework linking these findings to the mind–brain
    processes that mediate them. This framework suggests that the neuropsychological
    processes that mediate placebo effects may be crucial for a wide array of therapeutic
    approaches, including many drugs.

  • Identifiant unique
    10.1038/nrn3976
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